ES631010: 4-Methylumbelliferyl α(GlcNAcβ(1-4)Man) – www.a-radio.net

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ES631010: 4-Methylumbelliferyl α(GlcNAcβ(1-4)Man)

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Description

ES631010: 4-Methylumbelliferyl α(GlcNAcβ(1-4)Man)C24H31NO13 541. 5 A 4 methylumbelliferyl glycoside of a GlcNAc1 4Man disaccharide, mimicking the inner N glycan substructure released by endo mannosidase activity. Used as a fluorogenic substrate for mannosidases and N glycan processing enzymes acting on this linkage; enzymatic cleavage releases 4 methylumbelliferone. 4 Methylumbelliferyl (MU) glycosides are fluorogenic enzyme substrates: cleavage of the glycosidic bond by the target enzyme releases

C31H43D9O3 / 481

/ MUC1(126-149)-STn(131

9 / An Fmoc-protected L-serine building block carrying a GlcNAcβ1-3GalNAcα disaccharide

Fmoc-Thr(beta-D-Cel)-OH (Peracetate)

Fmoc-Ser((Ac)3-α-L-Fuc)-OH

β-D-GlcNAc-Propyl-Azide

developing therapeutic interventions

2-Azidoethyl β-D-galactopyranoside

Fmoc-Thr(α-D-Man(Ac)4)-OH

Fmoc-Ser(β-L-Fuc(Ac)3)-OH

and biological activity

25-diol-d6

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