AG142010: α-GalNAc-Butyl-Carboxy Methyl Ester

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Description

AG142010: α-GalNAc-Butyl-Carboxy Methyl EsterC14H25NO8 335. 35 An D N acetylgalactosamine (GalNAc) ligand equipped with a methyl ester protected carboxylic acid through a short butyl spacer. The methyl ester serves as a stable, protected form of the carboxylic acid that can be hydrolyzed under mild basic conditions (e. g., LiOH, NaOH) to unmask the free acid for downstream activation to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and subsequent coupling to amine functionalized platforms or

2-Aminoethyl 2-acetamido-2-deoxy-β-D-glucopyranoside

65 / / 1-α

C28H40N2O11 / 580

/ β-D-Glc-Ethyl-Azide / β-Glc-Et-N3

58 / A peracetylated β-D-N-acetylgalactosamine (GalNAcβ) ligand equipped with an amine-functionalized linker through a pentyl spacer

5-Aminopentyl 2-acetamido-2-deoxy-β-D-galactopyranoside

β-D-Lac(Ac)7-Et-N3

β-D-Gal-Propyl-Azide

Neu5Acα(2-6)GalNAc-Thr-NH-Biotin

The terminal GalNAcα residue is also a substrate for glycosyltransferases

β-D-LacNAc-C4-COOH

36 / A β-D-N-acetylgalactosamine (GalNAcβ) ligand equipped with an amine-functionalized linker through a pentyl spacer